The following is an excerpt....
BASICS
Description
A disorder during which patients experience urgency ± urge incontinence, usually accompanied by frequency and/or nocturia in the absence of causative infection or identified pathologic conditions
Epidemiology
- ~16% of men and women over 40 suffer from OAB
- In patients >75 yr, the prevalence increases to 31% of women and 42% of men.
Risk Factors
- Caucasian
- Insulin-dependent diabetes mellitus
- Depression
- Age >75
- Arthritis
- Increased BMI
General Prevention
- High-fiber diet
- Limited consumption of caffeine and alcohol
Pathophysiology
Overactivity of detrusor muscle:
- Neurogenic (eg, MS, Parkinson disease, stroke, spinal cord lesions, trauma)
- Myogenic (eg, aging, chronic bladder outlet obstruction, diabetes)
- Idiopathic
- Transient causes (DIAPPERS acronym):
- Delirium
- Infection
- Atrophic urethritis/vaginitis
- Pharmaceutical
- Psychological
- Excessive urine output
- Restricted mobility
- Stool impaction ...
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