Acromegaly is a rare endocrinologic disease characterized by excess secretion of growth hormone (GH), resulting in a syndrome of coarsened facial features and overgrowth of the hands and feet.
Enlarging shoe and ring size
Vision changes, particularly temporal hemianopsia
Hand numbness/carpal tunnel syndrome
Transsphenoidal surgery is the initial treatment of choice for most patients with acromegaly of pituitary origin, particularly if the tumor compresses the optic chiasm.
Surgery is associated ...
Every 3 to 4 months
Cardiovascular exam and BP measurement
Measurement of serum IGF-1
MRI of pituitary sel...
Dekkers OM, Biermasz NR, Pereira AM et al. Mortality in acromegaly: a metaanalysis. J Clin Endocrinol Metab. 2008;93(1):61–67. [View Abstract on OvidInsights]
Melmed S. Medical...
74107003 Acromegaly (disorder)
240089002 Myopathy in acromegaly (disorder)
230581008 Neuropathy in acromegaly...
The onset of acromegaly is insidious and may be initially subtle.
The serum IGF-1 level is the preferred screening test and is elevated in acromegaly.
An elevated IGF-1 should prompt an MRI of th...
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