Adenomyosis

Reviewed 06/2017
 


BASICS

DESCRIPTION

  • Benign invasion of the endometrium into the myometrium, producing a diffusely enlarged uterus

  • Microscopically, there are ectopic, nonneoplastic endometrial glands and stroma surrounde...

DIAGNOSIS

Pelvic pain, dysmenorrhea, and an enlarged uterus are the usual cues that prompt imaging by ultrasound or MRI; endometrial or uterine biopsies may be indicated in some cases. 

HISTORY

  • Presenti...

TREATMENT

  • The mainstay of treatment has been surgical therapy.

  • Medical therapy shows promise in certain patients.

MEDICATION

  • The levonorgestrel-releasing intrauterine system (Mirena) has been shown to re...

ONGOING CARE

PATIENT EDUCATION

Adenomyosis, PubMed health, at http://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0024411/ 

PROGNOSIS

  • Adenomyosis is a benign proliferation of endometrial tissue.

  • Symptoms usually...

REFERENCES

Taran  FA, Stewart  EA, Brucker  S. Adenomyosis: epidemiology, risk factors, clinical phenotype and surgical and interventional alternatives to hysterectomy. Geburtshilfe Frauenheilkd. ...

ADDITIONAL READING

  • Benagiano G, Habiba M, Brosens I. The pathophysiology of uterine adenomyosis: an update. Fertil Steril.  2012;98(3):572–579.

  • Fedele L, Bianchi S, Frontino G. Hormonal treatmen...

CODES

ICD10

N80.0 Endometriosis of uterus 

ICD9

617.0 Endometriosis of uterus 

SNOMED

  • 76376003 endometriosis of uterus (disorder)

  • 237115002 Endometriosis of myometrium (disorder)

CLINICAL PEARLS

  • Adenomyosis is often asymptomatic.

  • Both TVUS and MRI are very accurate for the diagnosis of adenomyosis.

  • MRI is more sensitive than TVUS, particularly in differentiating adenomyosis from...

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