Alzheimer Disease

Jill Ann Grimes, MD Reviewed 06/2018
 


BASICS

DESCRIPTION

  • Alzheimer disease (AD) is the most common cause of dementia in the elderly.

  • Degenerative neurologic disease with progressive impairment in ≥2 years:

    • Memory, executive function, atten...

DIAGNOSIS

Degenerative neurologic disease with progressive impairment in ≥2 areas
  • Memory, executive function, attention, language, or visuospatial skills AND

  • Significant interference in ability to fun...

TREATMENT

GENERAL MEASURES

  • Optimize treatment of associated comorbid conditions (including hearing and vision loss).

  • Analyze environment for safety and security and avoid sudden changes in environment.

  • H...

ONGOING CARE

FOLLOW UP RECOMMENDATIONS

Patient Monitoring

  • Schedule regular follow-up (3 months) to assess medical complications, provide support for family, and assess need for placement.

  • Serial mental s...

REFERENCES

1 McKhann GM, Knopman DS, Chertkow H, et al. The diagnosis of dementia due to Alzheimer’s disease: recommendations from the National Institute on Aging-Alzheimer’s Association workgroups o...

ADDITIONAL READING

  • Birks JS, Grimley Evans J. Rivastigmine for Alzheimer’s disease. Cochrane Database Syst Rev.  2015;(4):CD001191.  [View Abstract]

  • Buckley JS, Salpeter SR. A risk-benefit assess...

SEE ALSO

Depression; Hypothyroidism, Adult; Substance Use Disorders 

CODES

ICD10

  • G30.9 Alzheimer’s disease, unspecified

  • G30.0 Alzheimer’s disease with early onset

  • G30.1 Alzheimer’s disease with late onset

  • F02.81 Dementia in oth diseases classd elswhr w behavioral disturb

  • G3...

CLINICAL PEARLS

  • Daily intellectual stimulation, such as puzzles, and moderate physical exercise may help prevent AD.

  • Imaging studies have low yield in patients with a history typical of AD.

  • Encourage fa...

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