Necrotizing infections of the skin and fascia—necrotizing cellulitis and necrotizing fasciitis (NF)
NF is a rapidly spreading and potentially fatal infection in the fascia, with secon...
Symptoms often progress rapidly (over hours), requiring high index of suspicion, particularly if there are no clear risk factors.
Rapidly spreading skin lesions
Prompt and wide surgical débridement is the cornerstone of treatment.
Hyperbaric oxygen (HBO) has been used as an adjunct to antibiotics and surgical débridement.
May require ICU care
Monitor for clinical signs indicating need for repeated débridement.
Antibiotic therapy should be administered until further débrideme...
Carapetis JR, Jacoby P, Carville K et al. Effectiveness of clindamycin and intravenous immunoglobulin, and risk of disease in contacts, in invasive group A streptococcal infections....
M72.6 Necrotizing fasciitis
L03.90 Cellulitis, unspecified
A48.0 Gas gangrene
N49.3 Fournier gangrene
728.86 Necrotizing fasciitis
682.9 Cellulitis and abscess of unspecified sites
040.0 Gas ...
Necrotizing infections are associated with potentially life-threatening, rapidly progressive, widespread fascial necrosis.
NF may be mono- or polymicrobial.
Consider necrotizing soft tissue infec...
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