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Avian Flu

Sheila M. Seed, PharmD, MPH, RPh and George M. Abraham, MD, MPH, FACP Reviewed 06/2018
 


BASICS

DESCRIPTION

  • Human infection due to avian influenza type A viruses (subtypes H5N1 and H7N9 to date). H5N1 is highly pathogenic; H7N9 has low pathogenicity.

  • Presents with influenza-like illness and...

DIAGNOSIS

HISTORY

  • Close contact with suspected or confirmed case

  • Close contact with infected poultry

  • Recent travel (within 10 days) to high-risk area

  • Primary phase: H5N1 (*both H5N1 and H7N9)

    • Influenza-lik...

TREATMENT

Treat patients with suspected avian flu with immediate neuraminidase inhibitors, pending results of diagnostic lab tests (within 24 to 48 hours after exposure). 

GENERAL MEASURES

  • Minimize spre...

ONGOING CARE

PATIENT EDUCATION

PROGNOSIS

Mortality rate is high in aggressive H5N1 cases with median time to...

REFERENCES

1
Beigel JH, Farrar J, Han AM, et al; for Writing Committee of the World Health Organization (WHO) Consultation on Human Influenza A/H5. Avian influenza A (H5N1) infection in humans. N Engl ...

ADDITIONAL READING

CODES

ICD10

  • J09.X2 Flu due to ident novel influenza A virus w oth resp manifest

  • J09.X9 Flu due to ident novel influenza A virus w oth manifest

  • J09.X1 Influenza due to identified novel influenza A virus w...

CLINICAL PEARLS

  • Consider avian influenza in patients presenting with acute febrile respiratory illness and recent travel to high-risk areas (especially Asia) or who have spent time on poultry farms.

  • Os...

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