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Bartonella Infections

Robert Ellis, MD and Carrie Lynn Ellis, DVM, MS Reviewed 06/2018
 


BASICS

DESCRIPTION

  • Fastidious intracellular anaerobic gram-negative bacilli:

    • >30 distinct species, at least 13 known to cause disease in humans (1,2)

    • Bartonella henselae and Bartonella quintana are mo...

DIAGNOSIS

HISTORY

  • Typical CSD (up to 90% of cases)

    • Several days after inoculation, 2- to 3-mm nontender papules at the trauma site progress to reddened vesicles with or without crust.

    • Tender regional ade...

TREATMENT

Many cases of CSD are self-limited; antibiotic treatment guided by clinical presentation and disease severity 

MEDICATION

  • Antipyretics and analgesics for symptom management

  • Antibiotic choice de...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

Immunocompromised patients have increased risk for relapse. Extended periods of antibiotics are recommended. 

DIET

No diet modifications needed 

PATIENT EDUCATION

REFERENCES

1
Kaiser PO, Riess T, O'Rourke F, et al. Bartonella spp.: throwing light on uncommon human infections. Int J Med Microbiol.  2011;301(1):7–15. {L-End} [View Abstract on OvidMedline]
2
An...

ADDITIONAL READING

Prutsky G, Domecq JP, Mori L, et al. Treatment outcomes of human bartonellosis: a systematic review and meta-analysis. Int J Infect Dis.  2013;17(10):e811–e819. 

CODES

ICD10

  • A44.9 Bartonellosis, unspecified

  • A28.1 Cat-scratch disease

  • A79.0 Trench fever

  • A44.1 Cutaneous and mucocutaneous bartonellosis

  • A44.8 Other forms of bartonellosis

  • A44.0 Systemic bartonellosis

ICD9

  • 0...

CLINICAL PEARLS

  • Diagnosing Bartonella infections require a high degree of clinical suspicion.

  • CSD is self-limited in most immunocompetent patients.

  • Immunocompromised patients are at increased risk for c...

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