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Bladder Cancer

Margaret E. Thompson, MD, FAAFP Reviewed 06/2018
 


BASICS

DESCRIPTION

  • Primary malignant neoplasms arising in the urinary bladder

  • Most common type is transitional cell carcinoma (90%).

  • Other types include adenocarcinoma, small cell carcinoma, and squamous...

DIAGNOSIS

HISTORY

  • Painless hematuria is the most common symptom.

  • Urinary symptoms (frequency, urgency)

  • Abdominal or pelvic pain in advanced disease

  • Exposures (see “Risk Factors”)

PHYSICAL EXAM

Normal in ear...

TREATMENT

For nonmuscle-invasive bladder cancer, the treatment is generally removal via cystoscopic surgery (see earlier discussion on PDD). For muscle-invasive cancer, a radical cystectomy with pelvi...

ONGOING CARE

FOLLOW UP RECOMMENDATIONS

  • Superficial cancers

    • Urine cytology alone has not been shown to be sufficient for follow-up.

    • Cystoscopy every 3 months for 18 to 24 months, every 6 months for the ...

REFERENCES

1
1 National Cancer Institute. Cancer stat facts: bladder cancer. http://seer.cancer.gov/statfacts/html/urinb.html. Accessed July 7, 2017.
2
2 Freedman ND, Silverman DT, Hollenbeck AR, et al. ...

ADDITIONAL READING

  • Msaouel P, Koutsilieris M. Diagnostic value of circulating tumor cell detection in bladder and urothelial cancer: systematic review and meta-analysis. BMC Cancer.  2011;11:336....

SEE ALSO

  • Hematuria

  • Algorithm: Hematuria

CODES

ICD10

  • C67.9 Malignant neoplasm of bladder, unspecified

  • C67.4 Malignant neoplasm of posterior wall of bladder

  • C67.3 Malignant neoplasm of anterior wall of bladder

  • C67.0 Malignant neoplasm of trigone ...

CLINICAL PEARLS

  • Painless hematuria in smokers should be evaluated with cystoscopy.

  • Be aware of potential link between pioglitazone treatment and risk for bladder cancer.

  • The U.S. Preventive Services Tas...

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