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Cervical Malignancy

Olga L. Nunez, MD, Jean Khara Casillan, MD and Stuti Nagpal, MD, FAAFP Reviewed 06/2018
 


BASICS

DESCRIPTION

  • Invasive cancer of the uterine cervix

  • Most cervical cancers begin in the transformation zone. 60–75% of the cancers originate from squamous epithelium.

  • 25–40% of the cancers are adenoc...

DIAGNOSIS

HISTORY

  • Patient with HPV infection may be asymptomatic.

  • The most common symptom is postcoital vaginal bleeding.

  • Other symptoms include intermenstrual or postmenopausal bleeding and vaginal disc...

TREATMENT

GENERAL MEASURES

Improve nutritional state, correct anemia (Hb <12 g/dL), and treat any vaginal and/or pelvic infections. 

MEDICATION

  • Chemoradiation with cisplatin-containing regimen has sup...

ONGOING CARE

FOLLOW UP RECOMMENDATIONS

Patient Monitoring

  • With completion of definitive therapy and based on individual risk factors, patients are evaluated with physical/pelvic examinations:

    • Every 3 t...

REFERENCES

1
1 Committee on Practice Bulletins—Gynecology. ACOG Practice Bulletin Number 131: screening for cervical cancer. Obstet Gynecol.  2012;120(5):1222–1238. {L-End} {L-End} [View Abstra...

ADDITIONAL READING

  • American Society for Colposcopy and Cervical Pathology. Updated consensus guidelines for managing abnormal cervical cancer screening tests and cancer precursors. http://www.asccp.or...

SEE ALSO

Abnormal Pap and Cervical Dysplasia 

CODES

ICD10

  • C53.9 Malignant neoplasm of cervix uteri, unspecified

  • C53.0 Malignant neoplasm of endocervix

  • C53.1 Malignant neoplasm of exocervix

  • C53.8 Malignant neoplasm of overlapping sites of cervix uteri

ICD9

CLINICAL PEARLS

  • Cervical cancer is the second most common malignancy in women worldwide. Improving access to screening is likely to have the greatest impact in reduction of the burden of disease.

  • Women...

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