Coccidioidomycosis

Reviewed 06/2017
 


BASICS

DESCRIPTION

  • A pulmonary fungal infection endemic to the southwestern deserts of the United States:

    • Rarely progresses to involve extrapulmonary sites (<1%): bone, CNS, endocrine/metabolic, mu...

DIAGNOSIS

HISTORY

  • Thorough travel history is essential in pulmonary conditions not responding to normal measures.

  • Most humans infected with coccidioidomycosis are asymptomatic or have minimal symptoms (...

TREATMENT

GENERAL MEASURES

  • Cool mist humidifier for dry cough or sore throat, antitussives

  • Supportive therapy

  • Most cases resolve without antifungal treatment.

MEDICATION

FIRST LINE

  • In mild cases, treatment ...

ONGOING CARE

FOLLOWUP RECOMMENDATIONS

MONITORING

  • If serology is negative but index of suspicion is high, repeat every 2 weeks.

  • With positive serology, follow titers every 2 weeks until dropping or negati...

REFERENCES

Thompson GR 3rd. Pulmonary coccidioidomycosis. Semin Respir Crit Care Med.  2011;32(6):754–763. [View Abstract on OvidInsights]
Ruddy BE, Mayer AP, Ko MG et al. Coccidioidomyocosis in...

ADDITIONAL READING

  • Cadena J, Hartzler A, Hsue G et al. Coccidioidomycosis and tuberculosis coinfection at a tuberculosis hospital: clinical features and literature review. Medicine (Baltimore).  ...

CODES

ICD10

  • B38.9 Coccidioidomycosis, unspecified

  • B38.2 Pulmonary coccidioidomycosis, unspecified

  • B38.0 Acute pulmonary coccidioidomycosis

  • B38.1 Chronic pulmonary coccidioidomycosis

  • B38.89 Other forms of c...

PEARLS

  • Consider coccidioidomycosis in patients who travel to endemic areas and present with persistent pulmonary symptoms that do not respond to routine treatment.

  • Minimal exposure in an endemic area c...

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