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Cutaneous T-Cell Lymphoma, Mycosis Fungoides

Reviewed 06/2018
 


BASICS

Cutaneous T-cell lymphoma (CTCL) is a rare and typically indolent mature T-cell lymphoma presenting primarily in the skin. This disease involves overlap of the disciplines of dermatology, medic...

DIAGNOSIS

  • Diagnostic algorithm for MF is a point-based system. Points are scored for clinical, histopathologic, molecular biologic, and immunopathologic categories. A diagnosis of MF is made when a to...

TREATMENT

GENERAL MEASURES

  • Most cases are managed on an outpatient basis.

  • Treatment should be individualized for each patient, based on extent of disease and side effects of possible therapies.

  • Skin lesi...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

Must be individualized; includes routine physical exam with attention to skin lesions, lymphadenopathy, organomegaly; laboratory tests, includin...

REFERENCES

1
Wong HK. Novel biomarkers, dysregulated epigenetics, and therapy in cutaneous T-cell lymphoma. Discov Med.  2013;16(87):71–78. {L-End} [View Abstract on OvidMedline]
2
Agar NS, Wedgewo...

ADDITIONAL READING

  • Akilov OE, Geskin L. Therapeutic advances in cutaneous T-cell lymphoma. Skin Therapy Lett.  2011;16(2):1–5.

  • Alberti-Violetti S, Talpur R, Schlichte M, et al. Advanced-stage myco...

CODES

ICD10

  • C84.00 Mycosis fungoides, unspecified site

  • C84.08 Mycosis fungoides, lymph nodes of multiple sites

  • C84.09 Mycosis fungoides, extranodal and solid organ sites

  • C84.01 Mycosis fungoides, lymph no...

CLINICAL PEARLS

  • CTCL is a rare and typically indolent mature T-cell lymphoma presenting primarily in the skin; infiltration of activated and malignant T cells in the skin

  • MF, the most common subtype of...

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