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Dermatitis Herpetiformis

Abdul Aleem, MD and Hiral Shah, MD, FASGE, FACG Reviewed 06/2018
 


BASICS

DESCRIPTION

  • Dermatitis herpetiformis (DH) presents as a chronic, relapsing, polymorphous, intensely pruritic, erythematous papulovesicular eruption with symmetrical distribution primarily involv...

DIAGNOSIS

Diagnosis of DH involves a clinicopathologic correlation among clinical presentation, histologic and direct immunofluorescence (DIF) evaluation, serology, and response to therapy or dietary ...

TREATMENT

GENERAL MEASURES

  • GFD is the mainstay of treatment in DH and can lead to complete resolution of symptoms (1,2)[A].

  • Typically requires 18 to 24 months of strict adherence to GFD prior to resolut...

ONGOING CARE

FOLLOW UP RECOMMENDATIONS

Patient Monitoring

  • Every 6 to 12 months by physician and dietitian to evaluate GFD adherence and recurrence of symptoms

  • Adherence to GFD can be monitored with serol...

REFERENCES

1
1 Antiga E, Caproni M. The diagnosis and treatment of dermatitis herpetiformis. Clin Cosmet Investig Dermatol.  2015;8:257–265. {L-End} {L-End} [View Abstract on OvidMedline]
2
2 Bol...

ADDITIONAL READING

  • Bolotin D, Petronic-Rosic V. Dermatitis herpetiformis. Part I. Epidemiology, pathogenesis, and clinical presentation. J Am Acad Dermatol.  2011;64(6):1017–1024. {L-End} {L-En...

SEE ALSO

  • Celiac Disease

  • Algorithm: Rash

CODES

ICD10

L13.0 Dermatitis herpetiformis 

ICD9

694.0 Dermatitis herpetiformis 

SNOMED

111196000 Dermatitis herpetiformis (disorder) 

CLINICAL PEARLS

  • DH is a chronic, relapsing, intensely pruritic rash that often presents with erosions, excoriations, lichenification, and pigmentary changes secondary to scratching and healing of old ...

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