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Ductal Carcinoma In Situ

Bradley M. Turner, MD, MPH, MHA and David G. Hicks, MD Reviewed 06/2018
 


BASICS

DESCRIPTION

  • Ductal carcinoma in situ (DCIS) is a heterogeneous group of lesions that have in common the presence of a clonal proliferation of neoplastic epithelial cells confined to ducts and lo...

DIAGNOSIS

HISTORY

  • Most DCIS is now diagnosed by screening mammography (presence of microcalcifications in approximately 72%); patients may be asymptomatic with nonpalpable mass (12%) (1,2)[A].

  • Advanced ...

TREATMENT

SURGERY/OTHER PROCEDURES

  • Surgery is the primary treatment option. Options for surgery are based on risk of recurrence, anatomic location, extent of disease, and the ability to achieve “negati...

ONGOING CARE

FOLLOW UP RECOMMENDATIONS

  • History and physical exam every 6 to 12 months for the first 5 years and then annually

  • Mammography every 12 months (first mammogram 6 to 12 months after breast con...

REFERENCES

1 Siziopikou KP. Ductal carcinoma in situ of the breast: current concepts and future directions. Arch Pathol Lab Med.  2013;137(4):462–466.  [View Abstract]
2 Lee RJ, Vallow LA, McLa...

ADDITIONAL READING

  • Gøtzsche PC, Jørgensen KJ. Screening for breast cancer with mammography. Cochrane Database Syst Rev.  2013;(6):CD001877.  [View Abstract]

  • NCCN clinical practice guidelines in o...

SEE ALSO

Breast Cancer 

CODES

ICD10

  • D05.10 Intraductal carcinoma in situ of unspecified breast

  • D05.11 Intraductal carcinoma in situ of right breast

  • D05.12 Intraductal carcinoma in situ of left breast

  • R92.0 Mammographic microcalc...

CLINICAL PEARLS

  • DCIS is a heterogeneous group of noninvasive neoplastic lesions from breast ductal epithelial cells.

  • The incidence of DCIS has increased in women <50 and >70 years.

  • The goal of DCI...

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