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Endometrial Cancer and Uterine Sarcoma

Christina N. Kufel, DO, MS and Michael P. Hopkins, MD, MEd Reviewed 06/2018
 


BASICS

DESCRIPTION

  • Endometrial cancer: malignancy of the endometrial lining of the uterus

    • Two types

      • Type I: estrogen-dependent, grade 1 or grade 2, better prognosis, endometrioid histology

      • Type II: es...

DIAGNOSIS

HISTORY

  • Endometrial cancer

    • Postmenopausal bleeding is the most frequent sign. Any spotting or abnormal discharge mandates evaluation.

    • Premenopausal patients with history of anovulation and he...

TREATMENT

GENERAL MEASURES

  • Main treatment for uterine cancer is surgery.

  • Radiation is used to prevent tumor recurrence at the vaginal cuff.

MEDICATION

First Line

  • Endometrial

    • Chemotherapy for advanced or r...

ONGOING CARE

FOLLOW UP RECOMMENDATIONS

Follow-up visit with speculum and rectovaginal exam every 3 to 6 months for 2 years, then every 6 months for 3 years, and then annually for life (2)[C

Patient Monitoring

REFERENCES

1
1 Creasman W. Revised FIGO staging for carcinoma of the endometrium. Int J Gynaecol Obstet.  2009;105(2):109. {L-End} {L-End} [View Abstract on OvidMedline]
2
2 American College of O...

SEE ALSO

  • Cervical Malignancy

  • Algorithm: Pelvic Pain

CODES

ICD10

  • C54.1 Malignant neoplasm of endometrium

  • C55 Malignant neoplasm of uterus, part unspecified

  • C54.2 Malignant neoplasm of myometrium

  • C54.9 Malignant neoplasm of corpus uteri, unspecified

  • C54.3 Mal...

CLINICAL PEARLS

  • Most common presenting symptom is abnormal uterine bleeding.

  • Any patient with history of irregular, heavy, or prolonged periods should undergo endometrial biopsy.

  • Primary cause is unoppo...

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