Skip to main content

Glomerulonephritis, Postinfectious

Frances M. Rusnack, DO and Theodore B. Flaum, DO, FACOFP Reviewed 06/2018
 


BASICS

DESCRIPTION

Postinfectious glomerulonephritis (PIGN) is an immune complex disease associated with nonrenal infection by certain strains of bacteria, most commonly Streptococcus and Staphylococcu...

DIAGNOSIS

HISTORY

  • Patients present with acute nephritic syndrome, characterized by sudden onset of hematuria associated with edema and HTN 1 to 2 weeks after an infection.

  • A triad of edema, hematuria, a...

TREATMENT

MEDICATION

  • No specific therapy exists for PIGN, and no randomized controlled trials indicate that aggressive immunosuppressive therapy has a beneficial effect in patients with rapidly progres...

ONGOING CARE

FOLLOW UP RECOMMENDATIONS

Patient Monitoring

  • Repeat urinalysis to check for clearance of hematuria and/or proteinuria.

  • Consider other diagnosis if no improvement within 2 weeks.

  • Recurrence is...

REFERENCES

1
Nasr SH, Radhakrishnan J, D’Agati VD. Bacterial infection-related glomerulonephritis in adults. Kidney Int.  2013;83(5):792–803. [View Abstract on OvidMedline]
2
Nadasdy T, Hebert LA. ...

ADDITIONAL READING

  • Eison TM, Ault BH, Jones DP, et al. Post-streptococcal acute glomerulonephritis in children: clinical features and pathogenesis. Pediatr Nephrol.  2011;26(2):165–180. [View Ab...

CODES

ICD10

  • N05.9 Unsp nephritic syndrome with unspecified morphologic changes

  • N00.9 Acute nephritic syndrome with unsp morphologic changes

ICD9

580.0 Acute glomerulonephritis with lesion of proliferative...

CLINICAL PEARLS

  • PIGN is an immune complex disease occurring after infection with certain strains of bacteria, most commonly group A Streptococcus pyogenes.

  • The clinical presentation varies from asympto...

Subscribe to Access Full Content

Sign Up for a 10-Day Free Trial

Sign up for a 10-day FREE Trial now and receive full access to all content.

 
×