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Gout

David A. Ross, MD Reviewed 06/2018
 


BASICS

DESCRIPTION

  • Gout is an inflammatory arthritis related to a hyperuricemia (serum uric acid [SUA] level >6.8 mg/dL) (1).

  • Acute gouty arthritis can affect ≥1 joint; the 1st metatarsophalangeal jo...

DIAGNOSIS

HISTORY

  • Classic presentation of acute gouty arthritis:

    • Intense pain and tenderness in the 1st metatarsophalangeal joint (podagra)

    • Can occur in the midtarsal, ankle, or knee joints

    • Joint may be...

TREATMENT

GENERAL MEASURES

Topical ice as needed (5)[B

MEDICATION

  • Acute treatment

    • General principles:

      • Acute gouty arthritis attacks should be treated with pharmacologic therapy (5)[C].

      • Pharmacologic t...

ONGOING CARE

FOLLOW UP RECOMMENDATIONS

Patient Monitoring

  • SUA q2–5wk while titrating urate-lowering treatment to goal (1)[C]

  • Regularly monitor CBC, renal function, liver function test, and urinalysis.

DIET

REFERENCES

1
1 Khanna D, Fitzgerald JD, Khanna PP, et al; for American College of Rheumatology. 2012 American College of Rheumatology guidelines for management of gout. Part 1: systematic nonpharmacolo...

CODES

ICD10

  • M10.9 Gout, unspecified

  • M10.00 Idiopathic gout, unspecified site

  • M10.30 Gout due to renal impairment, unspecified site

  • M1A.30X0 Chronic gout due to renal impairment, unsp site, w/o tophus

  • M1A.9...

CLINICAL PEARLS

  • MSU crystals found in synovial fluid aspirate are pathognomonic for gout.

  • Pharmacologic treatment should begin within 24 hours of acute gout flare.

  • Asymptomatic hyperuricemia does not re...

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