Laryngeal Cancer

Sheila O. Stille, DMD and Hugh Silk, MD, MPH, FAAFP Reviewed 06/2018
 


BASICS

DESCRIPTION

  • A friable, granular squamous cell carcinoma of the larynx that leads to hoarseness, hemoptysis, and cough

  • System(s) affected: pulmonary; ear, nose, throat (ENT)

  • Synonym(s): cancer of t...

DIAGNOSIS

  • Early laryngeal cancer diagnosis generally has a good prognosis, with a 5-year disease-specific survival rate of >90% for T1 tumors (1)[A].

  • 35% are diagnosed at the localized stage (1)[A].

HISTORY

TREATMENT

  • Early laryngeal cancer (e.g., stage I or II) is often treated with single-modality therapy (1)[A]; no difference in overall survival between radiation therapy (XRT), open surgery, and endosc...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • Patient may remain fully active unless debilitated from more advanced disease and/or greater degree of surgery.

  • Reasons for posttreatment follow up:

    • Evaluation of t...

REFERENCES

Steuer CE, El-Deiry M, Parks JR, et al. An update on larynx cancer. CA Cancer J Clin.  2017;67(1):31–50.  [View Abstract]
Zhang D, Zhou J, Chen B, et al. Gastroesophageal reflux and c...

ADDITIONAL READING

  • D'Cruz AK, Sharma S, Pai PS. Current status of near-total laryngectomy: review. J Laryngol Otol.  2012;126(6):556–562.

  • Misono S, Marmor S, Yueh B, et al. T1 glottic carcinoma: d...

CODES

ICD10

  • C32.9 Malignant neoplasm of larynx, unspecified

  • C32.8 Malignant neoplasm of overlapping sites of larynx

  • C32.3 Malignant neoplasm of laryngeal cartilage

  • C32.0 Malignant neoplasm of glottis

  • C32.1...

CLINICAL PEARLS

  • Persistent hoarseness in an at-risk older person should prompt investigation with indirect and/or direct laryngoscopy.

  • XRT and multimodal therapies have reduced the need for laryngectom...

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