Acquired Hypothyroidism, Pediatric

Adda Grimberg Reviewed 06/2017



Hypothyroidism that occurs after the neonatal period 


  • May develop at any age

  • Autoimmune thyroid disorders occur more frequently in children and adolescents with type 1 diab...



  • Linear growth failure can be the first sign of thyroid dysfunction.

  • Declining school performance is a sensitive marker for lethargy and reduced focus.

  • Radiation exposure, history of typ...



l-Thyroxine (synthetic thyroid hormone) replacement 
  • Indicated for the treatment of overt or compensated hypothyroidism

  • 2–5 mcg/kg PO once daily

  • Monitor T4 and TSH and titrate dose to...

Ongoing Care

Follow-up Recommendations

Patient Monitoring

  • Whenever starting medication or adjusting dose, check T4 and TSH at 4–6 week intervals to assess adequacy of the new dose.

  • Once dose established,...

Additional Reading

  • Ai  J, Leonhardt  JM, Heymann  WR. Autoimmune thyroid diseases: etiology, pathogenesis, and dermatologic manifestations. J Am Acad Dermatol.  2003;48(5):641–659. [View Abstract...



  • 244.9 Unspecified acquired hypothyroidism

  • 244.8 Other specified acquired hypothyroidism

  • 245.2 Chronic lymphocytic thyroiditis

  • 246.8 Other specified disorders of thyroid


  • E03.9 Hypothyroidis...


  • Q: What happens if my child forgets a dose?

  • A: Give the dose as soon as you remember. If it is the next day, give 2 doses.

  • Q: How long will my child have to take these pills?

  • A: Probably for life.

  • Q: ...

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