Inadequate hydrocortisone secretion to meet body's stress requirement
Unresponsive to stimulation with adrenocorticotropic hormone (ACTH)
Weakness, tiredness, fatigue
Abdominal pain (can mimic acute abdomen)
Nausea or vomiting
Muscle or joint pains
Airway, breathing, and circulation management (ABCs)
BP support for hypotension:
Normal saline (0.9%) IV fluids 500 mL–1 L (peds: 20 mL/kg) bolus
All patients with acute adrenal insufficiency
ICU admission for patients with unstable or potentially unstable cases
Normal lab evaluation with t...
Acute adrenal insufficiency is a life-threatening emergency, and treatment should not be delayed in the ED while waiting for definite lab diagnosis.
Cancer of any type can present w...
Bouillon R. Acute adrenal insufficiency. Endocrinol Metab Clin N Am. 2006;35:767–775.
Kwon KT, Tsai VW. Metabolic emergencies. Emerg Med Clin N Am. 2007;25:1041–1060.
255.41 Glucocorticoid deficiency
255.5 Other adrenal hypofunction
E27.1 Primary adrenocortical insufficiency
E27.2 Addisonian crisis
E27.40 Unspecified adrenocortical insufficiency
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