Nonpruritic, well-demarcated, nonpitting edema of the dermis
Due to the release of inflammatory mediators that cause dilation and increased permeability of capillaries and venules:
A family history or history of recurrent episodes can be useful in the diagnosis. Use of culprit foodstuffs or medications, especially ACEIs should increase index of...
Establish IV access
Early intubation may be necessary due to the rapid progression of laryngeal swelling.
Administration of H1 blocker when available
Epinephrine to be considered fo...
Patients with systemic symptoms that do not resolve completely will need to be hospitalized for observation.
A monitored bed is recommended for those with airway ...
Early measures should be employed to maintain the patient's airway.
Consider use of newer agents in HAE patients (e.g., C1-INH and Kallikrein inhibition).
Austen K. Allergies, anaphylaxis, and systemic mastocytosis. In: Fauci AS, Braunwald E, Kasper DL, et al., eds. Harrison's Principles of Internal Medicine, 17th ed. New York, N...
277.6 Other deficiencies of circulating enzymes
995.1 Angioneurotic edema, not elsewhere classified
D84.1 Defects in the complement system
T78.3XXA Angioneurotic edema, initial encounter
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