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Disseminated Intravascular Coagulation, Emergency Medicine

Reviewed 06/2017
 


Basics

Description

  • Normal coagulation: Series of local reactions among blood vessels, platelets, and clotting factors

  • Disseminated intravascular coagulation (DIC) is systemic activation of coagulation a...

Diagnosis

Signs and Symptoms

  • Excessive bleeding:

    • Petechiae

    • Purpura

    • Hemorrhagic bullae

    • Wound bleeding

    • Bleeding from venipuncture/arterial lines

    • Epistaxis

    • Hemoptysis

    • GI bleeding

  • Excessive thrombosis:

    • Large vessels

    • ...

Treatment

Initial Stabilization/Therapy

  • Airway management and resuscitation measures:

    • Control bleeding

    • Establish IV access

    • Restore and maintain circulating blood volume.

  • Initiate therapy of precipitating d...

Follow-Up

Disposition

Admission Criteria

Severe precipitating illness in combination with DIC requires ICU admission. 

Discharge Criteria

None 

Followup Recommendations

Follow-up involves following platelet...

Pearls and Pitfalls

  • Suspect DIC as a complicating factor in severe, life-threatening illness.

  • Establish early clinical suspicion since the sequelae of DIC can be devastating.

  • Remember to consider treati...

Additional Reading

  • Bick  RL. Disseminated intravascular coagulation current concepts of etiology, pathophysiology, diagnosis, and treatment. Hematol Oncol Clin North Am.  2003;17(1):149–176.

  • Levi ...

Codes

ICD9

286.6 Defibrination syndrome 

ICD10

D65 Disseminated intravascular coagulation 

SNOMED

  • 67406007 Disseminated intravascular coagulation (disorder)

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