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Erythromelalgia

Reviewed 06/2018
 


BASICS

DESCRIPTION

  • Also known as “erythermalgia” and “Mitchell disease,” erythromelalgia (EM) is a clinical syndrome best described as chronic in nature that entails the hallmark symptoms of pain, eryt...

DIAGNOSIS

HISTORY

  • A history of pain, erythema, and increased temperature of the extremities, typically the feet

  • A family history of symptoms

  • A history of a condition or medication associated with seconda...

TREATMENT

GENERAL MEASURES

  • Avoid triggers: high environmental temperatures, alcohol use, heavy exercise, tight stockings, and shoes.

  • Symptomatic relief with elevation of the affected area and applicatio...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Intermittent complete blood counts to monitor for myeloproliferative disease

  • Observe for adverse reactions to pain management regimens, including...

REFERENCES

1
Davis MD, O'Fallon WM, Rogers RSIII, et al. Natural history of erythromelalgia: presentation and outcome in 168 patients. Arch Dermatol.  2000;136(3):330–336. {L-End} [View Abstract ...

CODES

ICD10

I73.81 Erythromelalgia 

ICD9

443.82 Erythromelalgia 

SNOMED

  • 37151006 Erythromelalgia (disorder)

  • 403390002 Primary erythromelalgia (disorder)

  • 403391003 Secondary erythromelalgia (disorder)

CLINICAL PEARLS

  • Consider EM in the differential diagnosis for patients presenting with hot and red feet or hands.

  • EM is associated with myeloproliferative diseases.

  • Patients often require several modali...

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