Bartter Syndrome, Pediatric

Elaine Ku and Anthony A. Portale Reviewed 06/2017
 


Basics

Description

  • Bartter syndrome is a hereditary renal salt-wasting tubulopathy characterized by hypokalemic, hypochloremic metabolic alkalosis and normal or low blood pressure.

  • The genetic defect is...

Diagnosis

History

  • Dehydration

  • Emesis

  • Diarrhea

  • Recurrent fevers

  • Failure to thrive

  • Polydipsia

  • Polyuria

  • Growth retardation

  • Anorexia

  • Symptoms of hypokalemia

    • Muscle weakness

    • Constipation

  • Cognitive and developmental del...

Treatment

Medication

Ongoing Care

Follow-up Recommendations

  • Frequent monitoring of serum electrolytes

  • Close follow-up of linear growth

  • Monitor for signs of kidney stone.

Prognosis

Can progress to chronic kidney disease or end-...

Additional Reading

  • Chadha  V, Alon  US. Hereditary renal tubular disorders. Semin Nephrol.  2009;29(4):399–411. [View Abstract]

  • Fremont  OT, Chan  JC. Understanding Bartter syndrome and Gitelman s...

Codes

ICD09

  • 255.1 Bartter’s syndrome

ICD10

  • E26.81 Bartter’s syndrome

SNOMED

  • 71275003 Pseudoprimary aldosteronism (disorder)

  • 700107006 Bartter syndrome antenatal type 1 (disorder)

  • 700109009 Bartter syndrome a...

FAQ

  • Q: Can Bartter syndrome be treated with renal transplantation?

  • A: Yes. A few cases of renal transplantation in Bartter syndrome have been described for correction of severe electrolyte disorders, g...

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