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Subject: Immunoglobulin D (IgD)
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IgD is mainly found on the surface of B cells and may help regulate B-cell function. IgD likely serves as an early B-cell antigen receptor; however, the function of the circulating IgD is largely unknown. IgD functions to activate some lymphocytes.
Normal value: ≤15.3 mg/dL.
Diagnosis of rare IgD myelomas (greatly increased)
IgD multiple myeloma
Chronic infection (moderately)
Acute viral hepatitis
After allogeneic bone marrow transplantation
Infancy, early childhood
An elevated IgD need to be identified as monoclonal or polyclonal by immunofixation method.