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Subject: Magnesium, Urine
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Magnesium is an important but commonly neglected electrolyte. Magnesium deficiency is often inadequately documented by serum magnesium levels. Urinary magnesium analyses have been advocated before and after therapeutic magnesium administration to further investigate the significance of apparent low serum magnesium. Abnormal levels of magnesium are most frequently seen in conditions or diseases that cause impaired or excessive excretion of magnesium by the kidneys or that cause impaired absorption in the intestines. Magnesium levels may be checked as part of an evaluation of the severity of kidney problems and/or of uncontrolled diabetes and may help in the diagnosis of GI disorders. Renal magnesium wasting occurs in renal transplant recipients who are on cyclosporine and prednisone. Renal conservation of magnesium is diminished by hypercalciuria, salt-losing conditions, and the SIADH.
Twenty-four–hour urine: 72–120 mg/day
Male: 18–110 mg/g creatinine
Female: 14–139 mg/g creatinine
Investigate chronic pancreas inflammation
Decreased blood magnesium
Insufficient magnesium intake
Magnesium forms insoluble complexes with normal urine constituents that precipitate as soon as urine is passed. Acidification is not required.
Urine concentration is diet dependent.
Magnesium depletion could be common condition found in 26% of hospitalized patients.
High concentrations of gadolinium are known to interfere with most metals tests.