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Subject: Mean Platelet Volume (MPV)
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MPV reflects the frequency distribution of platelet volumes.
Normal range: 7.8–11.0 fL.
MPV is used to evaluate variations in platelet size as related to various platelet abnormalities.
All cases of accelerated bone marrow production of platelets (immune thrombocytopenias, postchemotherapy)
Disorders associated with decreased platelet production
In some patients with sepsis
In some patients with inherited thrombocytopenias, such as Wiskott-Aldrich syndrome
Reference values appear to vary with the platelet count. MPV is affected by numerous variables related to specimen collection, the anticoagulant used, temperature, and duration of storage.