Plasminogen

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Subject: Plasminogen

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Definition

  • Plasminogen is the inactive, circulating precursor of plasmin, the final product of the fibrinolytic system. Therapy with plasminogen activators results in the generation of plasmin and intended thrombolysis.

  • Normal range: 70–113%.

Interpretation

Decreased In

  • Congenital: rare reported cases; may result in a predisposition to thrombosis

  • Acquired: severe DIC, pathologic fibrinolysis, or as the result of thrombolytic therapy, and in liver disease

 
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