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Natural steroid hormone that induces secretory changes in endometrium, promotes mammary gland development, relaxes uterine smooth muscles, blocks follicular maturation, and maintains pregnancy. Hormone synthesized by the ovary; low in follicular phase but increases to 10–40 mg/day during luteal phase and ≤300 mg/day if pregnancy occurs.
Normal range: see Table 16.68.
Detection of ovulation in the evaluation of the function of the corpus luteum
Monitoring patients having ovulation during induction with hCG, human menopausal gonadotropin, FSH/LH-releasing hormone, or clomiphene
To evaluate patients at risk for early abortion
Luteal phase of menstrual cycle
Luteal cysts of the ovary; ovarian tumors (e.g., arrhenoblastoma)
CAH caused by 21-hydroxylase, 17-hydroxylase, and 11-beta hydroxylase
Threatened abortion (some patients)
Toxemia of pregnancy