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Dermatitis Herpetiformis Reviewed 5/2014

Cindy England Owen, MD, Jewell Gaulding, MD, Caroline Nyenke Robinson, MD
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BASICS

  • Description
  • Epidemiology
  • Etiology and Pathophysiology
  • Risk Factors
  • General Prevention
  • Associated Conditions

DIAGNOSIS

  • History
  • Physical Exam
  • Differential Diagnosis
  • Tests

TREATMENT

  • Medication (Drugs)
  • Issues for Referral
  • Additional Therapies

ONGOING CARE

  • Follow-Up Recommendations
  • Diet
  • Patient Education
  • Prognosis
  • Complications
The following is an excerpt....
BASICS
Description
  • Dermatitis herpetiformis (DH) is a chronic, polymorphous, intensely pruritic, erythematous papulovesicular eruption with symmetrical distribution primarily involving extensor skin surfaces of the elbows, knees, buttocks, back, and scalp.
  • DH is a multifactorial disease with genetic, environmental, and immunologic influences.
  • DH is distinguished from other bullous diseases by characteristic histologic and immunologic findings, as well as associated gluten-sensitive enteropathy (GSE).
  • System(s) affected: Skin
  • Synonym(s): Duhring disease
Epidemiology
  • Occurs most frequently in those of Northern European origin
  • Rare in persons of Asian or African American origin
  • Predominant age: Most common in 4th decade, but may present at any age
  • Predominant sex: Male > Female (1.5:1 in the US, 2:1 worldwide)
Incidence

1/100,000 persons ...

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