The following is an excerpt....
BASICS
Description
- Myelodysplasia (spinal dysraphism, neural tube defect) is a very broad term encompassing a large heterogeneous group of congenital vertebral column defects that result from defects that occur during neural tube closure.
- This includes a group of developmental abnormalities that can be open (meningocele, myelomeningocele, lipomyelomeningocele) or closed (spina bifida occulta, posterior meningoceles, lipomyelomeningocele, and myelocystocele).
- Primary functional deficits can be lower limb paralysis and sensory loss, bladder and bowel dysfunction, and cognitive dysfunction.
- Affected children often have varying degrees of neurogenic bladder dysfunction.
ALERT:
Patients with myelodysplasia have a high incidence of latex allergy.
Epidemiology
- Open spinal dysraphism:
- 1 in every 1,000 births in US
- 2.5 times more common in whites than blacks
- Incidence decreasing over ...
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