Acromegaly: a rare endocrinologic disease characterized by excess secretion of growth hormone (GH), resulting in a syndrome of coarsened facial features and overgrowth of the jaw, ha...
Musculoskeletal
Enlarging shoe and ring size
Arthralgias/myalgias
Neurologic
Headache
Vision changes, particularly temporal hemianopsia
Hand numbness/carpal tunnel syndrome
Fatigue, weakness
...
Goals of treatment:
Decrease the serum IGF-1 level to within the reference range for the patient's age and sex.
Decrease the glucose-suppressed serum GH to <1 ng/mL.
Ameliorate symptoms with...
74107003 Acromegaly (disorder)
240089002 Myopathy in acromegaly (disorder)
230581008 Neuropathy in acromegaly (disorder)
80849007 Gigantism (diso...
The onset of acromegaly is insidious and may be initially subtle.
The serum IGF-1 level is the preferred screening test and is elevated in acromegaly.
An elevated IGF-1 should prompt an ...
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The clinical manifestations of acromegaly.
Acromegaly is characterized by enlargement of the facial features (nose, ears) and the hands and feet.