Primary adrenal gland insufficiency, which results from partial or complete (>90%) destruction of the adrenal cells with inadequate secretion of glucocorticoids and mineralocortic...
Anorexia, nausea, vomiting
Depression (60–80% of patients)
Decreased cold tolerance
Myalgia, flaccid muscle paralysis (hyperkal...
Salt, sugar, steroids, support, and search for a precipitating illness (usually infection, trauma, recent surgery, or...
Monitor BP, electrolytes, plasma renin, and fasting blood glucose level.
Periodically evaluate for long-term complications of corticosteroid use; screen for osteop...
E27.1 Primary adrenocortical insufficiency
A18.7 Tuberculosis of adrenal glands
E27.2 Addisonian crisis
255.41 Glucocorticoid deficiency
017.60 Tuberculosis of adrenal glands, unspecified
80% of cases are caused by an autoimmune process; the average age of diagnosis in adults is 40 years.
Consider the 5 S’s for the management of Addison disease: salt, sugar, steroids, su...
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FIG. 7.2. Addison disease. This teenager was referred to the emergency department with a diagnosis of anorexia nervosa. Patient has hyperpigmentation over the joints of his hands (A) and the spine (B).
FIG. 7.2. Addison disease. This teenager was referred to the emergency department with a diagnosis of anorexia nervosa. Patient has hyperpi...
<bold><italic>Figure 18-22</bold> Bronze skin pigmentation of Addison disease.</bold>