Primary adrenal insufficiency, also known as Addison disease, results from partial or complete (>90%) destruction of adrenal cells leading to inadequate secretion of glucocorticoi...
Anorexia, nausea, vomiting
Depression (60–80% of patients)
Decreased cold tolerance
Myalgia, flaccid muscle p...
Salt, sugar, steroids, support, and search for a precipitating illness (usually infection, trauma, recent surgery, or...
Monitor BP, electrolytes, plasma renin, and fasting blood glucose level.
Periodically evaluate for long-term complications of corticosteroid use; screen for osteop...
E27.1 Primary adrenocortical insufficiency
A18.7 Tuberculosis of adrenal glands
E27.2 Addisonian crisis
363732003 Addison’s disease (disorder)
186270000 Tuberculous Addison’s disease
80% of cases are caused by an autoimmune process; the average age of diagnosis in adults is 40 years.
Consider the 5 S’s for the management of Addison disease: salt, sugar, steroids, su...
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FIG. 7.2. Addison disease. This teenager was referred to the emergency department with a diagnosis of anorexia nervosa. Patient has hyperpigmentation over the joints of his hands (A) and the spine (B).
FIG. 7.2. Addison disease. This teenager was referred to the emergency department with a diagnosis of anorexia nervosa. Patient has hyperpi...
<bold><italic>Figure 18-22</bold> Bronze skin pigmentation of Addison disease.</bold>