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Adenomyosis

Bradley Turner, MD, MPH, MHA, FCAP, FASCP Reviewed 06/2020
 


BASICS

DESCRIPTION

  • Benign invasion of the endometrium into the myometrium, producing a diffusely enlarged uterus

  • Considered a specific entity in the PALM-COEIN FIGO (polyp; adenomyosis; leiomyoma; malig...

DIAGNOSIS

Pelvic pain, dysmenorrhea, and an enlarged uterus are the usual cues that prompt imaging by ultrasound or MRI; endometrial or uterine biopsies may be indicated in some cases. 

HISTORY

  • Presenti...

TREATMENT

  • There are no international guidelines to follow for medical or surgical treatment of adenomyosis.

  • The mainstay of treatment has been surgical therapy.

  • Medical therapy shows promise in certain ...

ONGOING CARE

PATIENT EDUCATION

PROGNOSIS

  • Adenomyosis is a benign proliferation of endometrial tissue.

  • Symptoms usua...

REFERENCES

1
Tan J, Yong P, Bedaiwy MA. A critical review of recent advances in the diagnosis, classification, and management of uterine adenomyosis. Curr Opin Obstet Gynecol.  2019;31(4):212–221.
...

ADDITIONAL READING

  • Buggio L, Monti E, Gattei U, et al. Adenomyosis: fertility and obstetric outcome. A comprehensive literature review. Minerva Ginecol.  2018;70(3):295–302.

  • Donnez J, Donnez O, Do...

CODES

ICD10

N80.0 Endometriosis of uterus 

ICD9

617.0 Endometriosis of uterus 

SNOMED

  • 76376003 endometriosis of uterus (disorder)

  • 237115002 Endometriosis of myometrium (disorder)

CLINICAL PEARLS

  • Adenomyosis is often asymptomatic.

  • MRI is more sensitive than TVUS, particularly in differentiating adenomyosis from leiomyoma. Differentiation of adenomyosis from leiomyoma is critical...

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