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Adenovirus Infections

Zaiba Jetpuri, MBA, FAAFP, DO and Nida Zahra, MD, FAAFP Reviewed 05/2023
 


BASICS

DESCRIPTION

  • Acute, typically self-limited, febrile illnesses characterized by inflammation of mucous membranes including the conjunctivae, respiratory, and GI tracts (1)[B]

  • Adenovirus infections...

DIAGNOSIS

Diagnosis is clinical 

HISTORY

Depends on type (see “Differential Diagnosis”); common symptoms with most respiratory forms: 
  • Headache, malaise

  • Sore throat

  • Cough, coryza

  • Fever (moderate to high)

  • Vom...

TREATMENT

GENERAL MEASURES

  • Treatment is supportive and symptomatic.

  • Infections are usually benign and short in duration.

MEDICATION

First Line

  • Acetaminophen 10 to 15 mg/kg PO for analgesia (Avoid aspirin.)

  • ...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Rest during febrile phases 

Patient Monitoring

For severe infantile pneumonia and conjunctivitis, daily physical exam until well 

DIET

No special diet 

PATIENT EDUCATION

REFERENCES

1
Ison MG, Hayden RT. Adenovirus. Microbiol Spectr. 2016;4(4). doi: 10.1128/microbiolspec.DMIH2-0020-2015.
2
Lion T. Adenovirus persistence, reactivation, and clinical management. FEBS Lett. 2...

ADDITIONAL READING

  • Centers for Disease Control and Prevention. Adenovirus symptoms. http://www.cdc.gov/adenovirus/about/symptoms.html. Accessed September 20, 2020. 

  • ...

SEE ALSO

Conjunctivitis, Acute; Intussusception; Pneumonia, Viral 

CODES

ICD10

  • B34.0 Adenovirus infection, unspecified

  • B30.1 Conjunctivitis due to adenovirus

  • J12.0 Adenoviral pneumonia

  • A08.2 Adenoviral enteritis

  • B30.2 Viral pharyngoconjunctivitis

SNOMED

  • 25225006 Disease due...

CLINICAL PEARLS

  • Adenovirus can mimic streptococcus pharyngitis with tonsillar exudates and cervical adenitis.

  • Adenovirus is the most common cause of strep-negative tonsillitis in young children.

  • Confirm...

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