An uncommon disorder in which proteins change conformation, aggregate, and form fibrils that infiltrate tissues, leading to organ dysfunction and increased risk of mortality. Deposit...
Four essential steps in diagnosing AL:
Considering the diagnosis based on presentation
Confirm diagnosis by tissue biopsy.
Determine the precursor protein.
Define the extent of involvemen...
Familial (ATTR): liver transplant to remove site of synthesis of the mutant protein
Hemodialysis and renal transplantation for renal amyloid
Hemodialysis-related amyloidosis: C...
Routine monitoring of renal function
Monitor adverse effects of medications.
AA: Maintenance of low SAA protein levels correlates to better outcom...
E85.9 Amyloidosis, unspecified
E85.3 Secondary systemic amyloidosis
E85.2 Heredofamilial amyloidosis, unspecified
E85.8 Other amyloidosis
E85.4 Organ-limited amyloidosis
E85.1 Neuropathic heredo...
The most commonly affected organs resulting in clinical symptoms are heart, kidneys, skin, peripheral and autonomic nerves, and liver.
Early detection is key to improved survival. Clini...
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