Necrotizing soft tissue infections (NSTI) are rare and rapidly progressing infections involving any layer of soft tissue, including skin, subcutaneous fat, fascia, and/or muscle (1)...
The most consistent finding is pain out of proportion to exam findings.
Early recognition and immediate initiation of treatment are key.
Most cases exhibit swelling and erythema.
Only 10...
Prompt surgical intervention is recommended for patients with signs of systemic toxicity or suspicion of necrotizing fasciitis (2).
Broad empiric antibiotic coverage (e.g., v...
May require ICU care
Monitor for clinical signs indicating need for repeated debridement.
Administer antibiotic therapy until debridement is no lo...
M72.6 Necrotizing fasciitis
L03.90 Cellulitis, unspecified
A48.0 Gas gangrene
N49.3 Fournier gangrene
52486002 Necrotizing fasciitis (disorder)
128045006 cellulitis (disorder)
80466000 Gas ...
NSTI are associated with potentially life-threatening, rapidly progressive, widespread necrosis.
Consider NSTI in patients with pain out of proportion to physical exam.
NSTI are a medica...
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