Otherwise known as anemia of chronic inflammation
During chronic systemic infection, inflammation, or malignancy, the production of proinflammatory mediators causes inhibition of eryt...
ACD is often discovered incidentally on routine CBC with differential.
ACD presents with the underlying causative infectious, inflammatory, or malignant process without any source of o...
Primary management should focus on the underlying cause of ACD (1).
Treatment of the primary disease will generally restore Hgb back to baseline.
In cases where primary treatm...
Besarab A, Bolton WK, Browne JK, et al. The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving...
D63.1 Anemia in chronic kidney disease
D63.8 Anemia in other chronic diseases classified elsewhere
234347009 Anemia of chronic disease
191268006 Chronic anemia
ACD is the second most common anemia seen clinically.
One of the most common diagnostic problems is making the distinction between ACD, IDA, and combined ACD + IDA.
Iron level is usually...
Sign up for a 10-day FREE Trial now and receive full access to all content.
FIGURE 41.7. The peripheral blood smear of refractory anemia with ringed sideroblasts is characterized by a dimorphic red cell population. A distinct population of hypochromic, often microcytic erythrocytes can be found admixed with normochromic, normocytic, or macrocytic erythrocytes.
FIGURE 41.7. The peripheral blood smear of refractory anemia with ringed sideroblasts is characterized by a dimorphic red cell population....
<bold>FIGURE 16-7</bold> Iron deficiency anemia. A peripheral smear shows hypochromic and microcytic erythrocytes. Poikilocytosis (irregular shape) and anisocytosis (irregular size) are often observed.
<bold>FIGURE 16-7</bold> Iron deficiency anemia. A peripheral smear shows hypochromic and microcytic erythrocytes. Poikilocyto...
Microcyte SIZE: Less than 6.5 ? CELL TYPE: Mature red blood cell DESCRIPTION: Smaller than normal cell; MCV usually less than 80 fL; have a central pallor; normochromic or hypochromic CLINICAL CONDITIONS: Iron deficiency anemia Thalassemias Lead poisoning Anemia of chronic disease Sideroblastic anemia
Microcyte SIZE: Less than 6.5 ? CELL TYPE: Mature red blood cell DESCRIPTION: Smaller than normal cell; MCV usually less th...
Iron Deficiency Anemia (IDA) White cells Not remarkable Platelets Normal or slightly increased Red cells Hb and Hct decreased Microcytic, hypochromic anemia Reticulocytes normal or slightly increased Increased RDW Pencil or cigar shaped red cells, codocytes Bone marrow Normoblastic hyperplasia Absent hemosiderin Decreased sideroblasts (less than 10%) Normoblasts are smaller than normal with ragged rims of cytoplasm containing little h...
Iron Deficiency Anemia (IDA) White cells Not remarkable Platelets Normal or slightly increased Red cells Hb and Hct decrease...
Microangiopathic Hemolytic Anemia White cells Not remarkable Platelets Decreased Red cells Normocytic, normochromic anemia Increased reticulocytes Schistocytes Polychromatophilia Peripheral Smear
Microangiopathic Hemolytic Anemia White cells Not remarkable Platelets Decreased Red cells Normocytic, normochromic anemia ...
<bold><italic>Figure 11-8</bold> The blood in iron deficiency anemia. A.</bold> Normal blood smear. <bold>B.</bold> Blood smear in iron deficiency anemia. The red cells are small (microcytic) and pale (hypochromic).
<bold><italic>Figure 11-8</bold> The blood in iron deficiency anemia. A.</bold> Normal blood smear. <bold>B....
<bold>FIGURE 20-8. Microcytic hypochromic anemia caused by iron deficiency.</bold> Red blood cells are significantly smaller than the nucleus of a lymphocyte.
<bold>FIGURE 20-8. Microcytic hypochromic anemia caused by iron deficiency.</bold> Red blood cells are significantly smaller t...