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Angioedema

Kathryn M Brown, MS, MD and Katherine Montag Schafer, BCACP, PharmD Reviewed 06/2021
 


BASICS

  • All patients presenting with angioedema should be treated with antihistamine, corticosteroids and if needed, epinephrine.

  • If angioedema thought to be related to allergen exposure, to prevent rec...

DIAGNOSIS

  • AAE:

    • Lack of positive family history of AE

    • Assess for:

      • Exposure to common allergens: foods, (shellfish, nuts, eggs, milk, wheat soy), latex, insect bites/stings, medicatio...

TREATMENT

GENERAL MEASURES

  • Intubation if airway is threatened (4)[C]

  • Eliminate suspected trigger (3)[C].

  • Volume replacement is essential for patients who are unstable or refractory to initial therapy ...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Diagnostic workup if symptoms are severe, persistent, or recurrent

  • For those with recurrent AE, specialty management is recommended.

DIET

Avoid ide...

REFERENCES

1
Cicardi M, Aberer W, Baneri A et at. Classification, diagnosis, and approach to treatment for angioedema: consensus report from the Hereditary Angioedema International Working Group. Aller...

SEE ALSO

Anaphylaxis; Urticaria 

CODES

ICD10

  • T78.3XXA Angioneurotic edema, initial encounter

  • D84.1 Defects in the complement system

SNOMED

  • 41291007 angioedema (disorder)

  • 82966003 Hereditary angioneurotic edema (disorder)

  • 402388007 Allergic...

CLINICAL PEARLS

  • AE is an acute, localized swelling of skin, mucosa, and submucosa caused by extravasation of fluid into the affected tissues.

  • If AE occurs in the presence of wheals, the patients should...

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