Rheumatoid arthritis (RA) is a chronic inflammatory disease primarily causing synovial inflammation and leading to the destruction of bone and cartilage (1).
Classification: based on...
Symmetric s...
Cush JJ. Rheumatoid arthritis: early diagnosis and treatment. Med Clin North Am. 2021;105(2):355–365.
Sánchez-Flórez JC, Seija-Butna...
M06.9 Rheumatoid arthritis, unspecified
M05.60 Rheu arthritis of unsp site w involv of organs and systems
M05.30 Rheumatoid heart disease w rheumatoid arthritis of unsp site
M05.70 Rheu arthri...
Early treatment with DMARDs is essential. Treat to target approach.
Methotrexate is the first-line treatment for active disease and glucocorticoids are used for flares if patients are a...
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Rheumatoid arthritis. (A) The hyperplastic synovium from a patient with rheumatoid arthritis shows numerous finger-like projections, with focal pale areas of fibrin deposition. The brownish color of the synovium reflects hemosiderin accumulation derived from old hemorrhage. (B) A microscopic view reveals prominent lymphoid follicles (Allison - Ghormley bodies), synovial hyperplasia and hypertrophy, villous folds, and thickening of the synovial membrane by fibrosis and inflammation. (C) A hi...
Rheumatoid arthritis. (A) The hyperplastic synovium from a patient with rheumatoid arthritis shows numerous finger-like projections, with ...
Rheumatoid nodule. (A) A patient with rheumatoid arthritis has a mass on a digit. (B) A microscopic view of a rheumatoid nodule shows a central area of necrosis surrounded by palisaded macrophages and a chronic inflammatory infiltrate.
Rheumatoid nodule. (A) A patient with rheumatoid arthritis has a mass on a digit. (B) A microscopic view of a rheumatoid nodule shows a ce...
FIGURE 50.4 Rheumatoid arthritis. (A) Early. (B) Advanced.
Radiographs of the MCP joints of a patient with rheumatoid arthritis demonstrate loss of joint space and some overlap of the metacarpal head on the proximal phalanx, indicating early palmar subluxation of the proximal phalanx. These findings are usually seen in a progressive fashion, with the radial side being worse.
Radiographs of the MCP joints of a patient with rheumatoid arthritis demonstrate loss of joint space and some overlap of the metacarpal he...
Swan-neck deformity of the index finger in a patient with rheumatoid arthritis. Hyperextension of the proximal interphalangeal (PIP) joint and flexion deformities of the metacarpophalangeal (MCP) and distal interphalangeal (DIP) joints.
Swan-neck deformity of the index finger in a patient with rheumatoid arthritis. Hyperextension of the proximal interphalangeal (PIP) joint...
A: A 55-year-old female with a type III deformity secondary to rheumatoid arthritis.
FIGURE 26.4. Gross appearance of chronic interstitial pneumonia in rheumatoid arthritis. Zones of honeycombing can be seen in the posterior subpleural regions. Some contraction and thickening of the lung also are noted, along with pleural thickening.
FIGURE 26.4. Gross appearance of chronic interstitial pneumonia in rheumatoid arthritis. Zones of honeycombing can be seen in the posterio...
<bold>FIG. 65.12.</bold> Destructive arthritis of an isolated distal interphalangeal joint with osteolysis of the proximal phalanx.
<bold>FIG. 65.12.</bold> Destructive arthritis of an isolated distal interphalangeal joint with osteolysis of the proximal pha...
<bold>FIG. 65.14.</bold> Prominent metatarsophalangeal joint involvement with subluxation and cupping of the base of the proximal phalanges. The big toe distal interphalangeal joint shows characteristic marginal erosions.
<bold>FIG. 65.14.</bold> Prominent metatarsophalangeal joint involvement with subluxation and cupping of the base of the proxi...
FIGURE 19-11.?Advanced rheumatoid arthritis. The hands show swelling of the joints and deviation of the fingers.
Figure 10-5 <bold>INFLAMMATORY VERSUS DEGENERATIVE ARTHRITIS.A. Inflammatory Arthritis (Rheumatoid Arthritis).</bold> The most prominent feature is the uniform bicompartmental loss of joint space.<bold> B. Degenerative Arthritis (Degenerative Joint Disease).</bold> In contrast, selective loss of a single compartment joint space in a non-uniform manner is apparent.<bold><italic>COMMENT:</bold></bold> This is an important differential feature between inflammatory and degenerative joint changes.
Figure 10-5 <bold>INFLAMMATORY VERSUS DEGENERATIVE ARTHRITIS.A. Inflammatory Arthritis (Rheumatoid Arthritis).</bold> The most...