A spectrum of diseases caused by species of the ubiquitous mold, Aspergillus
Saprophytic: chronic pulmonary aspergillosis (CPA), aspergilloma, chronic cavitary, chronic fibrosing, chr...
Symptoms depend on the site of infection and may include fever, dyspnea, cough, sinus congestion/pain.
Brownish/black sputum in half of patients with ABPA
Patients may develop pleuritic...
ABPA may improve with allergen avoidance and optimal asthma control.
Depending on the clinical picture, treatment of aspergilloma may include observation, oral antifungal ther...
ABPA: serum IgE levels (goal: to decrease levels by 25–50%), CXR, pulmonary function test, every 6 to 8 weeks to objectively assess for remissio...
B44.9 Aspergillosis, unspecified
B44.1 Other pulmonary aspergillosis
B44.81 Allergic bronchopulmonary aspergillosis
B44.89 Other forms of aspergillosis
B44.0 Invasive pulmonary aspergillosis
B44...
Although Aspergillus spp. are ubiquitous, most immunocompetent people do not acquire disease.
Diagnosis of aspergillosis can be challenging and is based on history, physical exam, and a...
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Aspergillus fungus ball. The lung contains a cavity filled with a fungus ball.
Allergic bronchopulmonary aspergillosis. A dilated bronchus is filled with a mucous plug, which has dense layers of eosinophilic infiltrates.
Allergic bronchopulmonary aspergillosis. A dilated bronchus is filled with a mucous plug, which has dense layers of eosinophilic infiltrat...
Invasive aspergillosis. A section of lung impregnated with silver shows branching fungal hyphae surrounding blood vessels and invading the adjacent parenchyma.
Invasive aspergillosis. A section of lung impregnated with silver shows branching fungal hyphae surrounding blood vessels and invading the...
<bold>Fig C 42-5. Allergic bronchopulmonary aspergillosis.</bold> This woman with a history of asthma shows impaction of dilated large airways, producing the "finger-in-glove" sign (large arrows). There is also impaction of dilated small airways, producing the "tree-in-bud" pattern (small arrows).<sup>63</sup>
<bold>Fig C 42-5. Allergic bronchopulmonary aspergillosis.</bold> This woman with a history of asthma shows impaction of dilat...