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Bladder Cancer

Margaret E. Thompson, MD Reviewed 06/2020
 


BASICS

DESCRIPTION

  • Primary malignant neoplasms arising in the urinary bladder

  • Most common type is transitional cell carcinoma (90%).

  • Other types include adenocarcinoma, small cell carcinoma, and squamous...

DIAGNOSIS

HISTORY

  • Painless hematuria is the most common symptom.

  • Urinary symptoms (frequency, urgency)

  • Abdominal or pelvic pain in advanced disease

  • Exposures (see “Risk Factors”)

PHYSICAL EXAM

Normal in ear...

TREATMENT

For non–muscle-invasive bladder cancer, the treatment is generally removal via cystoscopic surgery (see earlier discussion on PDD). For muscle-invasive cancer, a radical cystectomy with pelv...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • Superficial cancers

    • Urine cytology alone has not been shown to be sufficient for follow-up.

    • Cystoscopy every 3 months for 18 to 24 months, every 6 months for the ...

REFERENCES

1
National Cancer Institute Surveillance, Epidemiology, and End Results Program. https://seer.cancer.gov/statfacts/html/urinb.html. Accessed July 30, 2019. [View Abstract on OvidMedline]
2
Fre...

ADDITIONAL READING

  • Msaouel P, Koutsilieris M. Diagnostic value of circulating tumor cell detection in bladder and urothelial cancer: systematic review and meta-analysis. BMC Cancer.  2011;11:336....

CODES

ICD10

  • C67.8 Malignant neoplasm of overlapping sites of bladder

  • C67 Malignant neoplasm of bladder

  • C67.6 Malignant neoplasm of ureteric orifice

  • C67.1 Malignant neoplasm of dome of bladder

  • C67.9 Maligna...

CLINICAL PEARLS

  • Painless hematuria should be evaluated with cystoscopy.

  • Be aware of potential link between pioglitazone treatment and risk for bladder cancer.

  • The U.S. Preventive Services Task Force rec...

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