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Bladder Cancer

Veronica A. Torres, MD and LILY T. LUC, MD Reviewed 06/2022
 


BASICS

DESCRIPTION

  • Primary malignant neoplasms arising in the urinary bladder

  • There are 3 types that begin in cells in the lining of the bladder: transitional cell carcinoma, squamous cell carcinoma, an...

DIAGNOSIS

HISTORY

  • Painless hematuria is the most common symptom.

  • Urinary symptoms (frequency, urgency, dysuria)

  • Abdominal or pelvic pain in advanced disease

  • Exposures (see “Risk Factors”)

PHYSICAL EXAM

Norm...

TREATMENT

For nonmuscle-invasive bladder cancer, the treatment includes a complete TURBT and a single dose of intravesical chemotherapy; additional intravesical chemotherapy depends on risk of recurre...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • Superficial cancers

    • Urine cytology alone has not been shown to be sufficient for follow-up.

    • Cystoscopy every 3 months for 18 to 24 months, every 6 months for the ne...

REFERENCES

1
Li HT, Duymich CE, Weisenberger DJ, Liang G. Genetic and Epigenetic Alterations in Bladder Cancer. Int Neurourol J. 2016;20(Suppl 2):S84-S94.
2
National Cancer Institute Surveillance, Epide...

ADDITIONAL READING

SEE ALSO

DeGeorge KC, Holt HR, Hodges SC. Bladder Cancer: Diagnosis and Treatment. Am Fam Physician. 2017 Oct 15;96(8):507-514.  

SEE ALSO

  • Hematuria

  • Algorithm: Hematuria

CODES

ICD10

  • C67.8 Malignant neoplasm of overlapping sites of bladder

  • C67 Malignant neoplasm of bladder

  • C67.6 Malignant neoplasm of ureteric orifice

  • C67.1 Malignant neoplasm of dome of bladder

  • C67.9 Maligna...

CLINICAL PEARLS

  • Painless hematuria should be evaluated with cystoscopy.

    • Do not perform cystoscopy or imaging in asymptomatic, never-smoking women < 50 years with microscopic hematuria with <25 RB...

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