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General Medicine

Breast Cancer

Fairouz L. Chibane, MD and Alicia H. Vinyard, DO Reviewed 06/2020
 


BASICS

Most commonly diagnosed cancer (CA) and the second most common cause of CA death for U.S. women 

DESCRIPTION

  • Malignant neoplasm of cells native to the breast—epithelial, glandular, or stroma

  • Types...

DIAGNOSIS

HISTORY

  • Painless lump in breast or axilla, breast pain, heaviness

  • Swelling, thickening, redness, or dimpling of the skin (sign of advanced BC)

  • Nipple discharge (bloody), erosion, or retraction

  • A...

TREATMENT

GENERAL MEASURES

  • Multiple treatment modalities surgery, radiation, chemotherapy, and hormone therapy

  • National Comprehensive Cancer Network (NCCN) provides clinical treatment guidelines for BC.

MEDICATION

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • Every 4 to 6 months for 5 years and then annually

  • No evidence to support the use of routine complete blood count, LFTs, “tumor markers,” bone scan, chest x-ray, li...

REFERENCES

1
American Cancer Society. Breast cancer facts & figures 2017–2018. Atlanta, GA: American Cancer Society; 2017.

CODES

ICD10

  • C50.52 Malignant neoplasm of lower-outer quadrant of breast, male

  • C50.929 Malignant neoplasm of unspecified site of unspecified male breast

  • C50.812 Malignant neoplasm of overlapping sites of ...

CLINICAL PEARLS

  • U.S. women; lifetime risk of 1 in 8

  • High alcohol use, high body mass index (BMI), and physical inactivity are modifiable risk factors.

  • Normal mammography does not exclude possibility of ...

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Related Images
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Carcinoma of the breast. Mammogram. An irregularly shaped, dense mass (arrows) is seen in this otherwise fatty breast.
Carcinoma of the breast. Mammogram. An irregularly shaped, dense mass (arrows) is seen in this otherwise fatty breast.
FIG. 5.2. Nipple inversion from breast cancer.
FIG. 5.2. Nipple inversion from breast cancer.
FIG. 12.4. Solid masses. A: Invasive lobular carcinoma. This small solid mass (arrow) has indistinct margins, an irregular shape, a nonparallel orientation, and posterior shadowing, all features of malignancy. B: Mixed invasive ductal and lobular carcinoma. This larger mass has all of the features characterizing the smaller version in A. In addition, the infiltrative nature of the cancer is seen in spicules (arrows) extending into the surrounding f...
FIG. 12.4. Solid masses. A: Invasive lobular carcinoma. This small solid mass (arrow) has indistinct margins, an irregular shape, a nonpara...
Mammogram of breast cancer (note the irregular shape and borders of the growth)
Mammogram of breast cancer (note the irregular shape and borders of the growth)
Pt s/p mastectomy for breast cancer with nodules in the chest wall (bx proven recurrent cancer)
Pt s/p mastectomy for breast cancer with nodules in the chest wall (bx proven recurrent cancer)
FIGURE 15-11.?Mammograms. Normal mammogram, left breast.
FIGURE 15-11.?Mammograms. Normal mammogram, left breast.
Paget disease of the nipple. An erythematous, scaly, and weeping "eczema" involves the nipple.
Paget disease of the nipple. An erythematous, scaly, and weeping "eczema" involves the nipple.
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