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Brucellosis

Sangili Chandran, MD, Rakan Al-Adwan, MD and Krystal Almazan, MD, MS Reviewed 04/2024
 


BASICS

DESCRIPTION

Pediatric Considerations
  • Systemic granulomatous bacterial infection caused by Brucella sp.

  • Causes febrile illness, characterized by intermittent or irregular fevers and night sweats (u...

DIAGNOSIS

HISTORY

  • Nonspecific systemic febrile illnesses 

  • Fever (often high, undulant—increased in afternoon and evening) (93%)

  • Myalgia (91%)

  • Night sweats (87%)

  • Back pain and arthralgia (86%)

  • Headache (81%)

  • ...

TREATMENT

GENERAL MEASURES

  • Report cases to local public health department

  • Supportive care

  • In milk-related or occupational outbreaks, case surveillance and public health reporting

  • Bed rest during febrile p...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Routine serologic testing is not generally useful for patient monitoring or guiding duration of therapy, particularly in endemic areas 

  • If serolo...

REFERENCES

1
Quereshi KA, Parvez A, Fahmy NA, et al. Brucellosis: epidemiology, pathogenesis, diagnosis and treatment—a comprehensive review. Ann Med. 2023;55(2):2295398. doi: 10.1080/07853890.2023.229...

SEE ALSO

CODES

ICD10

  • A23.9 Brucellosis, unspecified

  • A23.8 Other brucellosis

  • A23.0 Brucellosis due to Brucella melitensis

  • A23.2 Brucellosis due to Brucella suis

  • A23.1 Brucellosis due to Brucella abortus

  • A23.3 Brucell...

CLINICAL PEARLS

  • Brucellosis is challenging to diagnose and is a reportable disease.

  • Brucellosis is characterized by intermittent or irregular fevers, with symptoms ranging from subclinical disease to i...

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