Skip to main content

Candidiasis, Invasive

Saira Ajmal, MD and Nerissa Fernandes Reviewed 04/2024
 


BASICS

DESCRIPTION

Candida albicans and related species cause a variety of infections. Noninvasive candidal infections are common and can take many forms including esophagitis, vaginitis, onychomycosis...

DIAGNOSIS

  • Gold standard of diagnosis is positive blood culture

  • Beta-D-glucan assay is sensitive, but not specific for diagnosis of candidiasis as Beta-D-glucan is present in cells of different fungi. C...

TREATMENT

Inpatient care is recommended for hematogenously disseminated invasive candidiasis. 

GENERAL MEASURES

  • Begin empiric antifungal therapy

  • Remove all intravenous catheters if possible. Removing cen...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • Obtain follow-up blood cultures for all patients with candidemia once treatment is initiated and all catheters are removed to ensure eradication...

REFERENCES

1
Kullberg BJ, Arendrup MC. Invasive candidiasis. N Engl J Med. 2015;373(15):1445–1456. doi: 10.1056/NEJMra1315399.
2
Pappas PG, Kauffman CA, Andes DR, et al. Clinical Practice Guideline for t...

CODES

ICD10

  • B37.7 Candidal sepsis

  • P37.5 Neonatal candidiasis

  • B37.89 Other sites of candidiasis

  • B37.0 Candidal stomatitis

  • B37.49 Other urogenital candidiasis

  • B37.2 Candidiasis of skin and nail

  • B37.9 Candidias...

CLINICAL PEARLS

  • Consider invasive candidemia in high-risk febrile patients not responding to appropriate antibiotic treatment.

  • Start antifungal therapy on all candidemic patients within 24 hours of a p...

Subscribe to Access Full Content

Sign Up for a 10-Day Free Trial

Sign up for a 10-day FREE Trial now and receive full access to all content.

 
×