Cluster of symptoms mediated by the release of humoral factors secreted by carcinoid tumors:
The term carcinoid has fallen out of favor due to l...
Most NENs are asymptomatic and discovered incidentally during imaging, endoscopy, surgery, or autopsy.
Episodic flushing (85%)—clinical hallmark
Secretory diarrhea (80%)
Surgery is first-line treatment for localized GEP-NENs.
Surgical cure is unlikely in the presence of intra-abdominal and widespread metastases (2).
Treatment has evolved slowly due to lack of...
Bhattacharya S, Davar J, Dreyfus G, et al. Carcinoid Heart Disease.
Dasari A, Shen C, Halperin D, et al. Trends ...
E34.0 Carcinoid syndrome
D3A.8 Other benign neuroendocrine tumors
35868009 Carcinoid syndrome (disorder)
255046005 neuroendocrine tumor (disorder)
The term carcinoid has fallen out of favor. Neuroendocrine neoplasms (NENs) is preferred.
<10% of NENs produce symptoms, often leading to delays in diagnosis.
NENs are often misdiagno...
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Transthoracic echocardiogram recorded in a patient with carcinoid syndrome and tricuspid valve involvement. <bold>A:</bold> A right ventricular inflow tract view reveals diffusely thickened and immobile tricuspid valve leaflets (<italic>arrows</bold>). This image was recorded in early systole. Note the complete failure of coaptation of the leaflets, which results in severe tricuspid regurgitation, confirmed in an apical four-chamber view with color flow Doppler imaging <b>(B)...
Transthoracic echocardiogram recorded in a patient with carcinoid syndr...