Skip to main content

Celiac Disease

Michelle E Duffelmeyer, MD and Chelsea E Robitaille, MSPAS Reviewed 04/2024
 


BASICS

DESCRIPTION

  • A non-IgE mediated immune reaction to gliadin, a protein component of dietary gluten (found in wheat, barley, rye, and other grains) primarily affecting the small intestine in geneti...

DIAGNOSIS

HISTORY

  • Diarrhea and cramping are the most common GI symptoms.

  • Other symptoms include: Steatorrhea (fatty stools); abdominal pain or distension; nausea, vomiting, flatulence; weight loss, weak...

TREATMENT

GENERAL MEASURES

  • Gluten-free diet (GFD)—avoid wheat, barley, rye, and other grains that contain gluten.

    • Rice, corn, and nut flour are safe and palatable substitutes  (1).

    • Grains: uncontaminate...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

  • Consultation with a registered dietitian

  • Screen for osteoporosis and treat accordingly.

  • Follow-up with GI at 3 to 6 months for serology and 12 months for repeat bio...

REFERENCES

1
Husby S, Murray JA, Katzka DA. AGA clinical practice update on diagnosis and monitoring of celiac disease—changing utility of serology and histologic measures: expert review. Gastroenterol...

SEE ALSO

Algorithms: Diarrhea, Chronic; Malabsorption Syndrome 

CODES

ICD10

K90.0 Celiac disease 

SNOMED

  • 396331005 Celiac disease (disorder)

  • 61715008 Celiac disease with diffuse intestinal ulceration

CLINICAL PEARLS

  • Screen for celiac disease in patients with nonspecific GI symptoms, presumed IBS, dermatitis herpetiformis, unexplained transaminitis, or unexplained iron deficiency anemia.

  • Test total ...

Subscribe to Access Full Content

Sign Up for a 10-Day Free Trial

Sign up for a 10-day FREE Trial now and receive full access to all content.

 
×