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Cervical Malignancy

Olga L. Nunez, MD, Jean Khara G. Casillan, RN, MD and Stuti Nagpal, MD, FAAFP Reviewed 06/2019
 


BASICS

DESCRIPTION

  • Most cervical cancers begin in the transformation zone.

  • 60–75% are from squamous epithelium and 25–40% are glandular.

EPIDEMIOLOGY

Incidence

  • Cervical cancer is the second most common mal...

DIAGNOSIS

HISTORY

  • Patient with HPV infection may be asymptomatic. The most common symptom is postcoital vaginal bleeding. Other symptoms are intermenstrual or postmenopausal bleeding and vaginal discha...

TREATMENT

GENERAL MEASURES

Improve nutritional state, correct anemia (Hb <12 g/dL), and treat pelvic infections. 

MEDICATION

  • Chemoradiation with cisplatin-containing regimen has superior survival over...

ONGOING CARE

FOLLOW-UP RECOMMENDATIONS

Patient Monitoring

  • With completion of definitive therapy and based on individual risk factors, patients are evaluated with physical/pelvic examinations:

    • Every 3 to ...

REFERENCES

1
Committee on Practice Bulletins—Gynecology. ACOG Practice Bulletin Number 131: screening for cervical cancer. Obstet Gynecol.  2012;120(5):1222–1238. [View Abstract on OvidMedline]
2
In...

ADDITIONAL READING

  • Martin-Hirsch PP, Paraskevaidis E, Bryant A, et al. Surgery for cervical intraepithelial neoplasia. Cochrane Database Syst Rev.  2013;(12):CD001318. [View Abstract on OvidMedli...

CODES

ICD10

  • C53.9 Malignant neoplasm of cervix uteri, unspecified

  • C53.0 Malignant neoplasm of endocervix

  • C53.1 Malignant neoplasm of exocervix

  • C53.8 Malignant neoplasm of overlapping sites of cervix uteri

ICD9

CLINICAL PEARLS

  • Cervical cancer is the second most common malignancy in women worldwide. Improving access to screening is likely to have the greatest impact in reduction of the burden of disease.

  • Women...

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