Cervical cancer is a malignant neoplasm arising from the uterine cervix.
Most cervical cancers begin in the transformation zone.
60–75% are from squamous epithelium, and 25–40% are gla...
Patients with HPV infection may be asymptomatic. Early stages can be discovered incidentally as a result of cervical cancer screening.
The most common symptoms of cervical cancer are i...
Improve nutritional state, correct anemia (Hb <12 g/dL), and treat pelvic infections.
Lymph node evaluation is key to staging and treatment
Correction of urinary tract obstr...
With completion of definitive therapy and based on individual risk factors, patients are evaluated with physical/pelvic examinations:
Every 3 to ...
Jin YM, Liu SS, Chen J, et al. Robotic radical hysterectomy is superior to laparoscopic radical hysterectomy and open radical hysterectomy in the treatment of cervical ca...
Abnormal Pap and Cervical Dysplasia
C53.9 Malignant neoplasm of cervix uteri, unspecified
C53.0 Malignant neoplasm of endocervix
C53.1 Malignant neoplasm of exocervix
C53.8 Malignant neoplasm of overlapping sites of cervix uteri
Cervical cancer is the second most common malignancy in women worldwide. Improving access to screening is likely to have the greatest impact in the reduction of the burden of disease.
W...
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FIG. 3.85. Recurrent cervical carcinoma with vesicovaginal fistula. Fat-suppressed, gadolinium-enhanced T1-weighted image of pelvis demonstrates enhancing infiltrating pelvic tumor (<italic>arrow</bold>) and wide communication between bladder and vagina (<italic>arrowhead</bold>) allowing passage of high signal intensity gadolinium.
FIG. 3.85. Recurrent cervical carcinoma with vesicovaginal fistula. Fat-suppressed, gadolinium-enhanced T1-weighted image of pelvis demons...
<bold>Figure 6.15 Atypical squamous cells of undetermined significance (ASC-US).</bold> This Pap smear shows superficial-type squamous cells with mild nuclear enlargement and hyperchromasia. These features are suggestive but not diagnostic of a low-grade squamous intraepithelial lesion.
<bold>Figure 6.15 Atypical squamous cells of undetermined significance (ASC-US).</bold> This Pap smear shows superficial-type ...
<bold>Figure 6.16 Low-grade squamous intraepithelial lesion (Pap smear).</bold> These lesions show mildly dysplastic squamous cells with nuclear enlargement, hyperchromasia, and irregular nuclear contours that are more pronounced than in Figure 6.15.
<bold>Figure 6.16 Low-grade squamous intraepithelial lesion (Pap smear).</bold> These lesions show mildly dysplastic squamous ...
<bold>Figure 6.17 High-grade squamous intraepithelial lesion (Pap smear).</bold> The dysplastic cells seen in the center show a high nuclear-to-cytoplasmic ratio.
<bold>Figure 6.17 High-grade squamous intraepithelial lesion (Pap smear).</bold> The dysplastic cells seen in the center show ...
<bold>Figure 6.18 High-grade squamous intraepithelial lesion (Pap smear).</bold> A cluster of overlapping, markedly dysplastic cells forms a sheet. Note single, severely dysplastic cells.
<bold>Figure 6.18 High-grade squamous intraepithelial lesion (Pap smear).</bold> A cluster of overlapping, markedly dysplastic...
Pap smear 1. Close up view of cross section of upper vagina and cervix with applicator inserted into the endocervical canal. Arrows indicate a clockwise rotation to obtain sample.
Pap smear 1. Close up view of cross section of upper vagina and cervix with applicator inserted into the endocervical canal. Arrows indic...
Normal cervical Papanicolaou (Pap) smear. Large squamous cells from the superficial, and intermediate layers of the epithelium are illustrated. The cells have abundant cytoplasm, which varies in staining from pink to blue. The nuclei are small, and the nuclear-cytoplasmic ratio is low. The most superficial cells have pyknotic nuclei (arrows).
Normal cervical Papanicolaou (Pap) smear. Large squamous cells from the superficial, and intermediate layers of the epithelium are illustr...
Pap smear 2. Close up view of cross section of upper vagina and cervix with wooden or plastic spatula pressed against cervix, longer end introduced slightly into os. Arrow indicates rotation to obtain ectocervical sample.
Pap smear 2. Close up view of cross section of upper vagina and cervix with wooden or plastic spatula pressed against cervix, longer end i...
<bold><italic>Figure 21-12</bold> Pap smears. A:</bold> Normal. Large, flat cells with small nuclei. <bold>B:</bold> Dysplasia. Large, dark nuclei indicate damaged DNA; cytoplasmic halo indicates human papillomavirus (HPV) effect. <bold>C:</bold> Malignant. Compact cells with huge, irregular, dark nuclei indicate malignancy.
<bold><italic>Figure 21-12</bold> Pap smears. A:</bold> Normal. Large, flat cells with small nuclei. <bold>B...
<bold><italic>Figure 6-16</bold> Pap smear of the cervix.</bold> Many normal cells are present, which have small, uniform nuclei. Also present are clumps of malignant cells, which have large, dark nuclei.
<bold><italic>Figure 6-16</bold> Pap smear of the cervix.</bold> Many normal cells are present, which have small, ...