An acute infectious disease caused by the gram-negative bacterium Vibrio cholerae
Characterized by severe secretory, watery diarrhea with extreme fluid and electrolyte depletion, vomi...
History of travel to endemic area and exposure to contaminated food/water source
Abrupt onset of explosive, painless watery diarrhea (“rice-water stools”) without tenesmus
Abdominal dis...
Primary goal is to replenish fluid losses. With proper treatment, fatality rates are <1%.
Two phases of rehydration: initial and maintenance (4)[C]
Evaluate initial level of dehydration (c...
CDC. Cholera—vibrio cholerae infection—vaccines. https://www.cdc.gov/cholera/vaccines.html. Accessed September 28, 2021.
Hsueh BY, Waters CM. Combatin...
A00.9 Cholera, unspecified
A00.0 Cholera due to Vibrio cholerae 01, biovar cholerae
A00.1 Cholera due to Vibrio cholerae 01, biovar eltor
63650001 Cholera (disorder)
240349003 Cholera due...
Personal (food and water selection/preparation; hand hygiene) and public sanitation are the keys to cholera prevention.
The current cholera vaccine is not indicated to prevent routine t...
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<bold>FIGURE 16-2</bold> <bold>The pathogenesis of cholera and enterotoxigenic <i>Escherichia coli</i> (ETEC) infections.</bold> The organisms colonize the mucosal surface via microbial adhesins—for example, colonization factor antigen (Cfa) of enterotoxigenic <i>E. coli.</i> The factor that binds <i>V. cholerae</i> to cells is not clearly defined, but a toxin coregulated pilus (Tcp) causes the organisms to adhere to one another and form mic...
<bold>FIGURE 16-2</bold> <bold>The pathogenesis of cholera and enterotoxigenic <i>Escherichia coli</i> (ETE...
Figure 73.1. Electron photomicrograph of <italic>Vibrio cholerae</bold>.
Figure 73.3. Model of cholera toxin showing the five binding subunits surrounding a single active (<italic>A</bold>) subunit.