A complex physical illness characterized by a new or definitive onset of debilitating fatigue that persists for >6 months and significantly reduces a person’s ability to perform u...
Box 1...
No treatment yet proven effective by large randomized trials; recommendations based on expert opinion and standard symptom management (1),(2)
Focus on changes in lifestyle and insight, with a...
Yancey JR, Thomas SM. Chronic fatigue syndrome: diagnosis and treatment. Am Fam Physician. 2012;86(8):741–746. [View Abstract on OvidMedline]
No pharmacologic agents (e.g., antidepressants, immune modulators) have been shown to be consistently effective in treating CFS.
~70% of patients show improvement with CBT; 55% with GET...
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