A gram-positive, spore-forming anaerobic bacillus that releases toxins to produce clinical disease
Infection caused by Clostridium difficile is frequently associated with antibiotic u...
Age and underlying comorbidities
Recent antibiotic use
Diarrhea (defined as >3 stools in 24 hours) that is watery, foul-smelling, and sometimes bloody (1)
Fever (<10%), anorexia, n...
Antimotility agents are contraindicated.
Avoid indiscriminate use of antibiotics.
Proton pump inhibitors are associated with recurrent infection but have not been shown to be c...
Relapses of colitis occur in 15–30%.
Relapses typi...
Johnston BC, Ma SS, Goldenberg JZ, et al. Probiotics for the prevention of Clostridium difficile-associated diarrhea: a systematic review and meta-analysis. Ann Intern Med. 20...
008.45 Intestinal infection due to Clostridium difficile
186431008 Clostridium difficile infection (disorder)
423590009 Clostridium ...
C. difficile is spread by fecal–oral contact.
Alcohol-based hand sanitizers are ineffective against C. difficile. Wash hands with soap and water.
Testing and treatment of asymptomatic pa...
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